Jonathan has over twenty-five years experience using large-scale computing to advance science. His personal research has focused on astrophysical fluids with the DOE ASCI ASAP program and on bioinformatics with the Ontario Institute for Cancer Research. He has also worked to support other researchers at Canada’s largest HPC centre, SciNet, and as Compute Canada’s first CTO. He currently works at Toronto’s Hospital for Sick Children on the CanDIG project, helping build a federated platform for national-scale analysis of locally-controlled private genomics data to connect Canada’s health genomics data. He is very interested in tools that have the potential to make big scientific computing more productive and powerful, and occasionally blogs on these topics at http://www.dursi.ca