Wednesday, March 29
9:00 am-6:00 pm
Merkin Lobby and Auditorium
Large-scale human genetic studies have succeeded in identifying hundreds of thousands of variants associated with human diseases and traits. One of the grand challenges on the frontier of human genomics and health is to pioneer new scalable paradigms and technologies to systematically link these many variants to cellular programs and gene regulation networks driving complex disorders. This will enable a deep understanding of the genetically-anchored biological programs affected in diseases, lay the foundation for a new generation of rationally designed medicines, and benefit patients and societies across the globe. The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease is thrilled to host a symposium highlighting some of the important work and progress ongoing across the vibrant Broad Institute community in this domain. Please join us for an exciting day of science and discussions around this topic.
Co-chaired by Melina Claussnitzer and Kasper Lage
Agenda |
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8:30 am - 9:00 am |
Registration and breakfast available |
Merkin Lobby |
9:00 am - 9:10 am |
Welcome Remarks Melina Claussnitzer, MGH, HMS, Broad Institute; Kasper Lage, MGH, HMS, Broad Institute |
Broad Auditorium |
9:10 am- 9:30 am |
Introduction to the NNF Center at the Broad Institute Kasper Lage, MGH, HMS, Broad Institute |
Broad Auditorium |
9:30 am - 10:00 am |
Genetics Keynote Benjamin Neale, MGH, HMS, Broad Institute |
Broad Auditorium |
10:00 am - 10:55 am |
Session 1: Tech development and emerging technologies Speakers - Fei Chen, Harvard, Broad Institute; JT Neal, Broad Institute Chair- Ray Jones, Broad Institute |
Broad Auditorium |
10:55 am - 11:05 am |
Morning coffee break |
Merkin Lobby |
11:05 am - 11:35 am |
GRO Keynote Brad Bernstein, HMS, DFCI, Broad Institute |
Broad Auditorium |
11:35 am - 12:50 pm |
Session 2: Gene regulation Speakers - Kristin Ardlie, Broad Institute; Robin Andersson, University of Copenhagen; Jesse Engreitz, Stanford, Broad Institute Chair - Brad Bernstein, , HMS, DFCI, Broad Institute |
Broad Auditorium |
12:50 pm - 2:00 pm |
Lunch |
Merkin Lobby |
2:00 pm - 4:00 pm |
Session 3: Cellular phenotypes + disease clustering Speakers - Miriam Udler, MGH, Broad Institute; Melina Claussnitzer, MGH, HMS, Broad Institute; Elise Robinson, HSPH, Broad Institute; Bridget Wagner, Broad Institute Chair - Melina Claussnitzer, MGH, HMS, Broad Institute |
Broad Auditorium |
4:00 pm - 4:15 pm |
Afternoon coffee break |
Merkin Lobby |
4:15 pm - 5:00 pm |
Panel discussion Panelists - Melina Claussnitzer, MGH, HMS, Broad Institute; Mark Daly, MGH, HMS, Broad Institute; Jesse Engreitz, Stanford, Broad Institute; Jose Florez, MGH, HMS, Broad Institute Moderator - Kasper Lage, MGH, HMS, Broad Institute |
Broad Auditorium |
5:00 pm - 6:30 pm |
Poster Reception |
Merkin Lobby |
Please note that, in order to attend onsite events, all Broadies, visitors, and contractors
must be fully vaccinated.