Wednesday, March 29
9:00 am-6:00 pm 
Merkin Lobby and Auditorium

Large-scale human genetic studies have succeeded in identifying hundreds of thousands of variants associated with human diseases and traits. One of the grand challenges on the frontier of human genomics and health is to pioneer new scalable paradigms and technologies to systematically link these many variants to cellular programs and gene regulation networks driving complex disorders. This will enable a deep understanding of the genetically-anchored biological programs affected in diseases, lay the foundation for a new generation of rationally designed medicines, and benefit patients and societies across the globe. The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease is thrilled to host a symposium highlighting some of the important work and progress ongoing across the vibrant Broad Institute community in this domain. Please join us for an exciting day of science and discussions around this topic.

Co-chaired by Melina Claussnitzer and Kasper Lage



8:30 am - 9:00 am

Registration and breakfast available

Merkin Lobby

9:00 am - 9:10 am

Welcome Remarks

Melina Claussnitzer, MGH, HMS, Broad Institute; Kasper Lage, MGH, HMS, Broad Institute

Broad Auditorium

9:10 am- 9:30 am

Introduction to the NNF Center at the Broad Institute 

Kasper Lage, MGH, HMS, Broad Institute

Broad Auditorium

9:30 am - 10:00 am

Genetics Keynote

Benjamin Neale, MGH, HMS, Broad Institute

Broad Auditorium

10:00 am - 10:55 am

Session 1: Tech development and emerging technologies

Speakers - Fei Chen, Harvard, Broad Institute; JT Neal, Broad Institute

Chair- Ray Jones, Broad Institute

Broad Auditorium

10:55 am - 11:05 am

Morning coffee break

Merkin Lobby

11:05 am - 11:35 am

GRO Keynote

Brad Bernstein, HMS, DFCI, Broad Institute

Broad Auditorium

11:35 am - 12:50 pm

Session 2: Gene regulation

Speakers - Kristin Ardlie, Broad Institute; Robin Andersson, University of Copenhagen;  Jesse Engreitz, Stanford, Broad Institute

Chair - Brad Bernstein, , HMS, DFCI, Broad Institute

Broad Auditorium

12:50 pm - 2:00 pm


Merkin Lobby

2:00 pm - 4:00 pm

Session 3: Cellular phenotypes + disease clustering

Speakers - Miriam Udler, MGH, Broad Institute; Melina Claussnitzer, MGH, HMS, Broad Institute; Elise Robinson, HSPH, Broad Institute; Bridget Wagner, Broad Institute

Chair - Melina Claussnitzer, MGH, HMS, Broad Institute

Broad Auditorium

4:00 pm - 4:15 pm

Afternoon coffee break

Merkin Lobby

4:15 pm - 5:00 pm

Panel discussion

Panelists - Melina Claussnitzer, MGH, HMS, Broad Institute; Mark Daly, MGH, HMS, Broad Institute;  Jesse Engreitz, Stanford, Broad Institute; Jose Florez, MGH, HMS, Broad Institute

Moderator - Kasper Lage, MGH, HMS, Broad Institute

Broad Auditorium

5:00 pm - 6:30 pm

Poster Reception

Merkin Lobby


Please note that, in order to attend onsite events, all Broadies, visitors, and contractors
must be fully vaccinated.