Dr. Wagner is an Assistant Professor at The Steve and Cindy Rasmussen Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital, and in the Departments of Pediatrics and Biomedical Informatics at the Ohio State University College of Medicine. His research is focused on the development of tools and standards for advancing precision medicine and our knowledge of genomic alterations in cancers. Dr. Wagner recently received a Genomic Innovator award from the National Human Genome Research Institute (NHGRI) in support of his work to develop computable applications of genomic knowledge in clinical practice and is a co-lead of the BRIDGE Center Standards Core for the NIH Bridge2AI program. He serves as director of the international Variant Interpretation for Cancer Consortium (VICC; cancervariants.org), a GA4GH Driver Project, and co-leader of the GA4GH Variant Representation team.

Dr. Wagner has co-developed several precision medicine web tools, including the Drug-Gene Interaction Database (www.dgidb.org), the database of Clinical Interpretations of Variants in Cancer (CIViC; www.civicdb.org), and the VICC meta-knowledgebase (search.cancervariants.org). His research continues to explore new models and tools to address the challenges of variation and genomic knowledge representation, including his work as a lead designer of the GA4GH Variation Representation Specification (vrs.ga4gh.org) and the VICC Gene Fusion specification (fusions.cancervariants.org).