Poster ID
P-25
Poster Title
Shared standards, sovereign data: building Australia’s human omics research infrastructure
Authors
Benjamin Goudey — Australian BioCommons
Bernie Pope — Australian BioCommons
Conrad Leonard — Australian BioCommons
Guerdon Mukama — Australian BioCommons
Irene Hung — Australian BioCommons
Jeff Christiansen — Australian BioCommons
Jess Holliday — Australian BioCommons
Jesseka Chadderton — Australian BioCommons
Joshua Harris — Australian BioCommons
Julie Schumann — Australian BioCommons
Nagasri Alava — Australian BioCommons
Saumya Singh — Australian BioCommons
Yassaman Alavi — Australian BioCommons
Anurag Katariya — Australian Access Federation
Ayana Menorca — Australian Access Federation
Joel Seaman — Australian Access Federation
John Scullen — Australian Access Federation
Patrick Carnuccio — Australian Access Federation
Poornima Mani — Australian Access Federation
Ryan Paytes — Australian Access Federation
Sarah Thomas — Australian Access Federation
Angeline Veeneman — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Kamile Taouk — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Marie Wong — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Mark Cowley — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Youjin Shrestha — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Gawnesh Paatni — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Iggy Menzies — Garvan Institute of Medical Research
Katherine Champ — Garvan Institute of Medical Research
Leonard Goldstein — Garvan Institute of Medical Research
Maxime Hebrard — Garvan Institute of Medical Research
Peter Louka — Garvan Institute of Medical Research
Sarah Kummerfeld — Garvan Institute of Medical Research
Thanh Nguyen — Garvan Institute of Medical Research
Tim Ho — Garvan Institute of Medical Research
Tim Kallady — Garvan Institute of Medical Research
Andrew Howard — National Computational Infrastructure
Brian Davis — National Computational Infrastructure
David Monro — National Computational Infrastructure
David Peters — National Computational Infrastructure
Dmitry Degrave — National Computational Infrastructure
Kisaru Liyanage — National Computational Infrastructure
Matthew Downton — National Computational Infrastructure
Pravin Mangukia — National Computational Infrastructure
Warren Kaplan — National Computational Infrastructure
Horatio Davis — QIMR Berghofer Medical Research Institute
John Pearson — QIMR Berghofer Medical Research Institute
Miranda Vidgen — QIMR Berghofer Medical Research Institute
Nic Waddell — QIMR Berghofer Medical Research Institute
Scott Wood — QIMR Berghofer Medical Research Institute
Mark Taylor — University of Melbourne
Sara Attinger — University of Melbourne
Alan Tsui — University of Melbourne | PX4 Health
Gayle Philip — University of Melbourne | PX4 Health
Justine Underwood — University of Melbourne | PX4 Health
Malcolm McConville — University of Melbourne | PX4 Health
Nikeisha Caruana — University of Melbourne | PX4 Health
Olivia Carter — University of Melbourne | PX4 Health
Andrew Patterson — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Felipe Jiménez Ibarra — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Katrina Williams — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Marko Malenic — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Oliver Hofmann — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Ray Liu — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Roman Valls Guimerà — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
William Intan — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Ainsley Newson — University of Sydney
Minna Paltiel — University of Sydney
Bernie Pope — Australian BioCommons
Conrad Leonard — Australian BioCommons
Guerdon Mukama — Australian BioCommons
Irene Hung — Australian BioCommons
Jeff Christiansen — Australian BioCommons
Jess Holliday — Australian BioCommons
Jesseka Chadderton — Australian BioCommons
Joshua Harris — Australian BioCommons
Julie Schumann — Australian BioCommons
Nagasri Alava — Australian BioCommons
Saumya Singh — Australian BioCommons
Yassaman Alavi — Australian BioCommons
Anurag Katariya — Australian Access Federation
Ayana Menorca — Australian Access Federation
Joel Seaman — Australian Access Federation
John Scullen — Australian Access Federation
Patrick Carnuccio — Australian Access Federation
Poornima Mani — Australian Access Federation
Ryan Paytes — Australian Access Federation
Sarah Thomas — Australian Access Federation
Angeline Veeneman — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Kamile Taouk — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Marie Wong — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Mark Cowley — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Youjin Shrestha — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Gawnesh Paatni — Children's Cancer Instititute | Zero Childhood Cancer | Kids Cancer Centre
Iggy Menzies — Garvan Institute of Medical Research
Katherine Champ — Garvan Institute of Medical Research
Leonard Goldstein — Garvan Institute of Medical Research
Maxime Hebrard — Garvan Institute of Medical Research
Peter Louka — Garvan Institute of Medical Research
Sarah Kummerfeld — Garvan Institute of Medical Research
Thanh Nguyen — Garvan Institute of Medical Research
Tim Ho — Garvan Institute of Medical Research
Tim Kallady — Garvan Institute of Medical Research
Andrew Howard — National Computational Infrastructure
Brian Davis — National Computational Infrastructure
David Monro — National Computational Infrastructure
David Peters — National Computational Infrastructure
Dmitry Degrave — National Computational Infrastructure
Kisaru Liyanage — National Computational Infrastructure
Matthew Downton — National Computational Infrastructure
Pravin Mangukia — National Computational Infrastructure
Warren Kaplan — National Computational Infrastructure
Horatio Davis — QIMR Berghofer Medical Research Institute
John Pearson — QIMR Berghofer Medical Research Institute
Miranda Vidgen — QIMR Berghofer Medical Research Institute
Nic Waddell — QIMR Berghofer Medical Research Institute
Scott Wood — QIMR Berghofer Medical Research Institute
Mark Taylor — University of Melbourne
Sara Attinger — University of Melbourne
Alan Tsui — University of Melbourne | PX4 Health
Gayle Philip — University of Melbourne | PX4 Health
Justine Underwood — University of Melbourne | PX4 Health
Malcolm McConville — University of Melbourne | PX4 Health
Nikeisha Caruana — University of Melbourne | PX4 Health
Olivia Carter — University of Melbourne | PX4 Health
Andrew Patterson — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Felipe Jiménez Ibarra — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Katrina Williams — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Marko Malenic — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Oliver Hofmann — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Ray Liu — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Roman Valls Guimerà — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
William Intan — University of Melbourne | Collaborative Centre for Genomic Cancer Medicine
Ainsley Newson — University of Sydney
Minna Paltiel — University of Sydney
Abstract
Australia’s human omics research ecosystem spans autonomous institutions, data custodians, infrastructure providers, a federal system of government and multiple legal jurisdictions. Within this setting, the GUARDIANS program is taking a collaborative, standards-led approach to building national research infrastructure: aligning partners through shared technical standards, trusted implementation patterns, and clearly defined user needs.
Funded by Bioplatforms Australia through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS), and led by Australian BioCommons with national delivery partners, GUARDIANS is building connected capabilities for data discovery, identity and access management, data governance and authorisation, repositories and data commons, secure transfer, and scalable analysis. Technical standards and products from across the GA4GH Themes and Workstreams provide common reference points that help partners align while retaining appropriate institutional control over data, systems and governance.
Our design process begins with user journeys and use cases. The people whose needs shape the infrastructure include researchers, study participants, data custodians, data access committees, platform operators and infrastructure providers. The value of an individual system depends on how well it supports all connected pathways spanning service operation, data discovery, access request and approval, and analysis.
The poster will combine a national capability map, end-to-end user journeys and short partner case studies of working implementations. Together, they illustrate three lessons from the Australian experience. First, interoperability standards can provide a practical basis for coordination across institutions. Second, data sovereignty and custodian governance are core design requirements for trusted infrastructure. Third, requirements gathering, testing and iterative delivery are essential to building useful services that communities can adopt and sustain.
These lessons will be increasingly relevant as research draws on omics data generated through clinical care and national precision medicine settings, including Singapore’s PRECISE programme and Australia’s emerging precision-health agenda. GUARDIANS offers an Australian implementation case study and an invitation to the GA4GH community to help refine the standards, practices and international connections needed for the next phase.
Funded by Bioplatforms Australia through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS), and led by Australian BioCommons with national delivery partners, GUARDIANS is building connected capabilities for data discovery, identity and access management, data governance and authorisation, repositories and data commons, secure transfer, and scalable analysis. Technical standards and products from across the GA4GH Themes and Workstreams provide common reference points that help partners align while retaining appropriate institutional control over data, systems and governance.
Our design process begins with user journeys and use cases. The people whose needs shape the infrastructure include researchers, study participants, data custodians, data access committees, platform operators and infrastructure providers. The value of an individual system depends on how well it supports all connected pathways spanning service operation, data discovery, access request and approval, and analysis.
The poster will combine a national capability map, end-to-end user journeys and short partner case studies of working implementations. Together, they illustrate three lessons from the Australian experience. First, interoperability standards can provide a practical basis for coordination across institutions. Second, data sovereignty and custodian governance are core design requirements for trusted infrastructure. Third, requirements gathering, testing and iterative delivery are essential to building useful services that communities can adopt and sustain.
These lessons will be increasingly relevant as research draws on omics data generated through clinical care and national precision medicine settings, including Singapore’s PRECISE programme and Australia’s emerging precision-health agenda. GUARDIANS offers an Australian implementation case study and an invitation to the GA4GH community to help refine the standards, practices and international connections needed for the next phase.
Digital Poster