41

Bernard Pope - Australian BioCommons
Jessica Holliday - Australian BioCommons
Conrad Leonard - Australian BioCommons
Kylie Davies - Australian BioCommons
Irene Hung - Australian BioCommons
Joshua Harris - Australian BioCommons
Yassaman Alavi - Australian BioCommons
Jesseka Chadderton - Australian BioCommons
Jeff Christiansen - Australian BioCommons
Steven Manos - Australian BioCommons
Uwe Winter - Australian BioCommons
Julie Schumann - Australian BioCommons
Ben Goudey - Australian BioCommons
Guerdon Mukama - Australian BioCommons
Ryan Pytes – Australian Access Federation
Poornima Mani – Australian Access Federation
Mark Cowley - Children’s Cancer Institute
Marie Wong-Erasmus - Children’s Cancer Institute
Angeline Veeneman - Children’s Cancer Institute
Gawnesh Paatni - Children’s Cancer Institute
Kamile Touk - Children’s Cancer Institute
Youjin Shrestha - Children’s Cancer Institute
Ignatius Jeppe Menzies Garvan Institute of Medical Research
Katherine Champ - Garvan Institute of Medical Research
Leonard Goldstein - Garvan Institute of Medical Research
Maxime Hebrard - Garvan Institute of Medical Research
Peter Louka - Garvan Institute of Medical Research
Sarah Kummerfeld– Garvan Institute of Medical Research and UNSW – St Vincent’s Healthcare – Clinical School
Thanh Nguyen - Garvan Institute of Medical Research
Tim Ho - Garvan Institute of Medical Research
Tim Kallady - Garvan Institute of Medical Research
Amanda Shea - Garvan Institute of Medical Research and Murdoch Children's Research Institute
Caitlin Morrison - Garvan Institute of Medical Research and Murdoch Children's Research Institute
Caitlin Uren - Garvan Institute of Medical Research and Murdoch Children's Research Institute
Cas Simons - Garvan Institute of Medical Research and Murdoch Children's Research Institute
Warren Kaplan – National Computational Infrastructure
Kisaru Liyanage - National Computational Infrastructure
Matthew Downton - National Computational Infrastructure
Dmitry Degrave - National Computational Infrastructure
Wenjing Xue - National Computational Infrastructure
John Pearson - QIMR Berghofer Medical Research Institute
Nic Waddell - QIMR Berghofer Medical Research Institute
Scott Wood - QIMR Berghofer Medical Research Institute
Mark Taylor - University of Melbourne
Alan Tsui - University of Melbourne
Olivia Carter - University of Melbourne
Katrina Williams - University of Melbourne
Marko Malenic - University of Melbourne
Felipe Jiménez Ibarra - University of Melbourne
Roman Valls - University of Melbourne
William Intan - University of Melbourne
Florian Reisinger - University of Melbourne
Viktor Lin - University of Melbourne
Ray Liu - University of Melbourne
Andrew Patterson - University of Melbourne
Oliver Hofmann - University of Melbourne
Ainsley Newson – University of Sydney
Sara Attinger – University of Sydney
Minna Paltiel – University of Sydney

The GUARDIANS program (Genomics Uplift for Australia through Research Data Infrastructure At National Scale) is a national initiative to transform Australia’s capacity for secure, standards-aligned access to human genomics and related omics research data. Funded by Bioplatforms Australia through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS), GUARDIANS is coordinated by Australian BioCommons and delivered in partnership with leading organisations, including the Australian Access Federation, Children’s Cancer Institute, Garvan Institute of Medical Research, National Computational Infrastructure, QIMR Berghofer Medical Research Institute, The University of Melbourne and The University of Sydney.

The program has two iterative phases designed to provide direction and flexibility as delivery progresses. The initial phase focuses on establishing core infrastructure that enables researchers to more easily discover, access, and analyse Australian human omics datasets. Our Phase I outcomes aim to include live platforms with real data use cases, and established governance, demonstrating the value and feasibility of national-scale federation. The subsequent phase will extend infrastructure maturity, support broader community onboarding, and enable deeper integration with international data-sharing efforts.

Progress in Phase I is already visible across four program streams: core services and expertise; foundational infrastructure, data flagship projects; and innovation pilots. Teams are actively delivering shared infrastructure including identity and access management, data governance, and data resource management. Our work uses global standards including those from GA4GH, and incorporates technologies like Beacon and Gen3 to support discoverability, interoperability, and responsible data sharing. Ongoing collaboration and community demonstrations foster alignment and shared technical direction across the program.

GUARDIANS is committed to supporting the ongoing sustainability and coordination of Australia’s human genomics data ecosystem. By building on past efforts and guided by national priorities, GUARDIANS is enabling a future where Australian researchers can securely access and use nationally significant genomics data to accelerate biomedical research and clinical impact.