Name
Session 2: Mutations in the germline and across populations
Date & Time
Wednesday, April 23, 2025, 1:30 PM - 4:30 PM
Speakers
Kelley Harris, University of Washington
Molly Przeworski, Columbia University
David Reich, Harvard University
Shamil Sunyaev, Harvard Medical School
Sara Carioscia, Johns Hopkins University
Alexej Abyzov, Mayo Clinic
Arya Rao, Broad Institute of MIT and Harvard
Matthew Neville, Wellcome Sanger Institute
Mikhail Moldovan, Harvard Medical School
Molly Przeworski, Columbia University
David Reich, Harvard University
Shamil Sunyaev, Harvard Medical School
Sara Carioscia, Johns Hopkins University
Alexej Abyzov, Mayo Clinic
Arya Rao, Broad Institute of MIT and Harvard
Matthew Neville, Wellcome Sanger Institute
Mikhail Moldovan, Harvard Medical School
Description
Mutations acquired through life in germ cells have the potential to be passed on to the next generation, which - over time - will manifest as genetic variation between individuals and populations, affecting gene expression and regulation, and underpinning many genetic diseases. In this session, we will focus on the mutational processes and somatic evolution in germ cells, the evolutionary forces shaping inherited genetic variation and genetic disease.