Kidney-NExT5 
5th Annual Kidney-NExT Symposium

Thursday April 4, 2019
Broad Institute | Monadnock Room 
415 Main Street | Cambridge MA

 New Horizons for Kidney Therapeutics

Symposium Program

9:00 am Welcome
Todd Golub and Anna Greka
 

9:15 - 10:00 am
Keynote Lecture 1
Chair: Todd Golub
 

Big data and health outcomes: challenges and opportunities
Robert Califf
 

Session 1. Toward therapies for kidney diseases
 

Chair:  Amy Shulman and Opeyemi Olabisi
 

10:00 - 10:30 am
SGLT2 inhibitors for diabetic kidney disease
Jim List

10:30 - 11:00 am
Tolvaptan for polycystic kidney disease
Vincente Torres

11:00 - 11:30 am
New perspectives on endpoints and clinical trial design
Lesley Inker

Panel Discussion and Brainstorming Session:

How much progress have we made in kidney therapeutics? What can be done better?
Facilitator: Anna Greka
 

11:30 am - 12:30 pm
Panelists:

Dave White, patient advocate
Nicole Jefferson, patient advocate
Kimberly Smith, FDA
MeraTilley, Goldfinch Bio
Melissa West, Kidney Health Initiative
Eugene Rhee, MGH
Samir Parikh, BIDMC

12:30 - 1:15 pm
Lunch
 

Session 2. Frontiers: genomics, organoids and systems biology in the kidney space
Chairs: Brian Pereira and Joseph Bonventre
 

1:15 - 1:45 pm  
A systems biology approach to ciliopathies
Peter Jackson

1:45 - 2:15 pm   
A glomerulus on a chip: current technology and future directions
Samira Musah

2:15 - 2:45 pm   
Kidney organoids in drug development
Beno Freedman
 

2:45 - 3:15 pm   
A newly completed GWAS of diabetic kidney disease
Joanne Cole

3:15 - 3:30 pm
Coffee break

3:30 - 4:15 pm
Keynote Lecture 2
Chair: Krzystzof Kiryluk
 

Predicting risk for common deadly diseases from millions of genetic variants
Sekar Kathiresan

 

4:15 pm
Closing remarks

Anna Greka